Definitions
- Physical dependence: adaptive physiologic state; drug class specific withdrawal if abrupt drug d/c
- Tolerance: a state of adaptation in which ongoing exposure induces changes that result in lessening of one or more of the drug’s effects over time
- Addiction: primary, chronic, treatable, neurologic disease with impaired control over drug use, compulsive/continued use despite harm and craving
- Pseudoaddiction: behaviors that look like addiction motivated by inadequate pain relief
